The disease occurs more often in women (20-40 years), the chronic course. They appear plate foci initially red, then bold and and eventually atrophic, usually on the face, scalp, mouth, nose. The disease has a tendency to create new foci, which are to be merged. In 5% of cases without treatment develops systemic lupus erythematosus. It is used locally-anti-inflammatory therapy (topical corticosteroids), cryotherapy foci (freezing "snow" of carbon dioxide), in severe cases, is given to chloroquine. Long term therapy lasts about two years or is treatment carried out at intervals. Instead of chloroquine can be given hydroxychloroquine because of less risk of retinopathy. Therapeutic options are still and corticosteroids or retinoids, sulfones, azathioprine, and thalidomide. Also, it is necessary to avoid UV rays.
ponedjeljak, 16. studenoga 2015.
Discoid lupus erythematosus (DLE)
The disease occurs more often in women (20-40 years), the chronic course. They appear plate foci initially red, then bold and and eventually atrophic, usually on the face, scalp, mouth, nose. The disease has a tendency to create new foci, which are to be merged. In 5% of cases without treatment develops systemic lupus erythematosus. It is used locally-anti-inflammatory therapy (topical corticosteroids), cryotherapy foci (freezing "snow" of carbon dioxide), in severe cases, is given to chloroquine. Long term therapy lasts about two years or is treatment carried out at intervals. Instead of chloroquine can be given hydroxychloroquine because of less risk of retinopathy. Therapeutic options are still and corticosteroids or retinoids, sulfones, azathioprine, and thalidomide. Also, it is necessary to avoid UV rays.
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